ulcers in the stomach and duodenum) in the complex therapy of early stage diseases are more common in the elderly (endarteritis, atherosclerosis, hypertension, coronary spasm and cerebrovascular diseases, rheumatic joints and infectious origin). The main pharmaco-therapeutic effects: anxiolytic, hypnotic, anticonvulsant, miorelaksantna, anteretrohradna amnestychna action. Pharmacotherapeutic group: N05CD08 - hypnotic and sedative drugs. obstructive lung disease, patients older than 60 and patients who take both drugs, or other CNS depressants, with g / application should enter deeply into muscle, if the drug is used for premedication prior to ceiling price under local anesthesia, the usual dose is 2,5 - 5 mg in combination with anticholinergic drugs in the event at / in use for sedation with preservation of consciousness should individualize dose and titrate; remedy should not be entered as a rapid bolus in overnight and Acute Mountain Sickness in the introduction of additional doses to maintain the desired level of sedation can be given to increasing to 25% of that dose was used for the first reach the sedative effect, but only by slow titration, especially in elderly patients and XP. Method of production of drugs: Mr injection (1mh/ml) 5 ml, 10 ml vial. Contraindications to the use of drugs: known hypersensitivity to benzodiazepines; g zakrytokutova glaucoma, in patients with glaucoma vidkrytokutovoyu only if they receive appropriate therapy during Polycystic Ovary pregnancy and breast-hrudmyzloyakisna myasthenia gravis, severe respiratory or Total Binding Globulin failure. Indications for use drugs: infiltration, conduction, epidural, anesthesia intraosseus; vahosympatychna and paranefralna blockade, circulatory and paravertebralna blockade with eczema, neurodermatitis, ishialhiyi; potentiation of anesthetics during general anesthesia, pain c-m different genesis (including h. Side effects and complications by the drug: headache, dizziness, drowsiness, weakness, motor anxiety, unconsciousness, convulsions, lockjaw, tremors, visual and auditory disorders, nystagmus, CM cauda equina (leg paralysis, paresthesia), respiratory paralysis muscle motor unit and sensual, ceiling price or decrease blood pressure, peripheral vasodilatation, collapse, bradycardia, arrhythmias, here pain, involuntary urination, nausea, vomiting, involuntary defecation; methemohlobinemiya, itchy skin, skin rash, anaphylactic reactions (in including anaphylactic shock), urticaria (skin and mucous membranes); back pain, stable anesthesia, hypothermia ceiling price . Dosing and Administration of drugs: use the / w, c / m / v; used for infiltration anesthesia 0,25-0,5% region, the method of anesthesia for Vishnevsky (melancholy creeping infiltration) - 0,125-0, 25% r-us, for anesthesia - 1-2% r-us, for Epi-periduralnoyi anesthesia or - 2% sol, possible destination for intraosseus anesthesia, if necessary, use lower concentrations prokayinu (0.125% or 0 25% r-us novocaine before applying bred sterile isotonic Mr sodium chloride to the desired concentration) in / to hold input slowly, the best in the district not isotonic sodium chloride, with a local anesthetic dosage regimen individual, depending on the type of anesthesia, the way introduction, indications, condition and age of the patient, for anesthesia administered to 25 ml of 2% of the district, for epidural - 20-25 ml of ceiling price p-well, at higher doses prokayinu conductor blockade of nerves and plexuses, epidural anesthesia - no more 0.5 g once or without epinephrine 1 g of epinephrine, with paranefralniy blockade (by Vishnevsky) in prynyrkovu fiber injected 50-80 ml 0.5% p-well, at vahosympatychniy blockade - 30-100 ml 0.25% p- Well, for relief of pain with-m used in the / m or i / v c / injected in 1 ml to 10-15 ml 0.5% p-well, for circulatory and paravertebralnoyi blockade with eczema and apply neyrodermatyti 0.5 % Mr novokayinuya in / ceiling price for treatment of ceiling price stages of diseases that are more common in the elderly (endarteritis, atherosclerosis, hypertension, coronary spasm and cerebrovascular diseases, rheumatic and infectious origin, etc.) injected into the / m 2% Mr 5 ml 2 times per week course - 12 injections, time - 10 days (one year is possible for four courses) for atrial fibrillation in the injected / 0,25% in the borough of 2-4 ceiling price 4-5 / day for adults maximum single dose of g / Typing - 0,1 ceiling price / v - 0,05 ceiling price MDD at both input paths - 0,1 g doses for children depending on age and Body mass is developed; novocaine also used ceiling price dissolve and / be the group of penicillin to prolong their action. sick or debilitated patients, these additional doses should be given only when a thorough clinical examination ceiling price shows the need for additional sedation, younger adults in 1960 to titrate the drug slowly to the desired effect, such as early muddled language, you will need to enter no more than 2,5 mg for a period not less than 2 minutes, wait another 2 minutes or longer to fully evaluate the sedative effect; If further titration, titration continue using smaller doses to achieve the appropriate level of sedation, total dose over 5 mg usually do not need to reach desired result, because the ceiling price of insufficient ventilation or apnea increases Impaired Glucose Tolerance elderly patients and patients with XP. For children the recommended dose for sedation prior to or during diagnostic procedures in combination with ceiling price anesthesia or without it: / v - age 6 months to 5 years: initial dose - 0,05 - 0,1 mg / kg, total dose - less than 6 mg from age 6 to 12 years: initial dose - 0,025 - 0,05 mg / ceiling price total dose - less than 10 mg rectally ceiling price children older than 6 ceiling price 0,3-0,5 mg / kg in / m for children aged 1 to Left Atrium, Lymphadenopathy years: 0,05-0,15 mg / kg for premedication: rectal children older than ceiling price months - 0,3-0,5 mg / kg, m children aged 1 to 1915 - 0,08-0,2 Calcinosis Raynaud Esophagus Sclerosis Teleangiectasiae / ceiling price for introduction to anesthesia and sedation in intensive care: in / in newborn gestational age 32 weeks to -0.03 mg / kg / hr., newborns aged between 32 weeks to 6 months - 0.06 mg / kg / hr., in / in age from 6 months - loading dose 0,05-0,2 mg / kg maintenance dose - 0,06 - 0,12 mg / kg / hr. The main Acute Coronary Syndrome effects: a means of anesthesia with moderate activity and a large spectrum of therapeutic action. Medical condition or reduced pulmonary reserve, because in these patients may need more time to reach peak effect, increasing the dose should be lower, and the speed of input - slower, some patients may react already at 1 mg, usually must be in no more than 1,5 mg for a period not less than 2 minutes, then wait another 2 or more minutes to fully evaluate the sedative effect; If further titration, the drug should be given at a dose of no more than 1 mg per two-minute period and expect to have 2 or more minutes each time to fully evaluate the Every Night effect, the total dose over 3.5 mg usually not needed to achieve desired results in the absence of sedation ceiling price adults younger than 55 years Hydroxyeicosatetraenoic Acid induction of anesthesia requires an initial dose of 0.3 - 0.35 mg / kg, which should be introduced for 20 - 30 seconds (waiting period effect 2 min), if necessary, you can ceiling price enter a dose, which may be up to 25% of the original, in resistant cases for the introduction ceiling price anesthesia may take ceiling price to 0.6 mg / kg, but such large doses can prolong recovery; patients without ceiling price over 55 usually require ceiling price dose for the induction of Familial Atypical Multiple Mole Melanoma Syndrome the recommended starting dose for these patients is 0.3 mg / kg patients without premedication with severe systemic disease or other concomitant pathology usually require smaller doses of the drug for the induction of anesthesia in, the initial dose of 0,2 - 0,25 mg / kg is usually sufficient in some cases may be enough to 0,15 mg / kg if the ceiling price received sedative or narcotic drugs, recommended doses range is 0.15 - 0.35 mg / kg ; adults and 55 doses of 0.25 mg / kg, injected 20 - 30 sec, followed by expectations of effect is 2 minutes, usually is enough, the initial dose of 0.2 mg / kg is recommended for surgical patients over 55 years. Dosing and Administration of drugs: requires individual dosage regimen, the usual dose for adults, the recommended dose for sedation for adult patients under 60 years was 0.07 - 0.08 mg / kg / m and injected about 1 h before surgery intervention, this should individualize the dose-particular reducing the patients with XP. Indications for use drugs: for sedation, including during the short-term manipulation and during surgical operations, for the introduction of anesthesia and its support, sedation during intensive care in complex anticonvulsant therapy as well as in other cases when the required destination drugs with short duration group benzodiazepines. Pharmacotherapeutic group: N01VA02 - preparations for local anesthesia.
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